Semax

A synthetic peptide analog of a fragment of adrenocorticotropic hormone (ACTH), developed in Russia, where it has clinical use (not FDA-approved in the US). Studied for modulating BDNF (brain-derived neurotrophic factor) and neuroprotective pathways.

Cognitive function, focus, and neuroprotection research; historically studied for post-stroke recovery in Russian clinical settings.

Lyophilized. Research routes are typically intranasal or subcutaneous. Reconstitute per the general reference below.

General reconstitution & storage reference for lyophilized peptides:

1. 1Reconstitute with bacteriostatic water (0.9% benzyl alcohol) rather than plain sterile water — the preservative meaningfully extends usable shelf life.
2. 2In bacteriostatic water, refrigerate at 2–8°C, typically usable for ~28–30 days. In plain sterile water (no preservative): 7–14 days.
3. 3Lyophilized (unmixed) vials are stable at refrigerated or, for some peptides, frozen temperatures for extended periods prior to reconstitution.
4. 4Avoid repeated freeze-thaw cycles, direct light/UV exposure, and heat — these are the primary drivers of peptide degradation.
5. 5Reconstitute gently: inject the water down the inside wall of the vial and swirl — don't shake, which can denature the peptide structure.

Central-nervous-system-active compound — general peptide handling precautions apply, with added caution given CNS activity.

• Research literature — Semax nootropic